Journal article
Consensus Definition for Atrophy Associated with Age-Related Macular Degeneration on OCT: Classification of Atrophy Report 3
SR Sadda, R Guymer, FG Holz, S Schmitz-Valckenberg, CA Curcio, AC Bird, BA Blodi, F Bottoni, U Chakravarthy, EY Chew, K Csaky, RP Danis, M Fleckenstein, KB Freund, J Grunwald, CB Hoyng, GJ Jaffe, S Liakopoulos, JM Monés, D Pauleikhoff Show all
Ophthalmology | ELSEVIER SCIENCE INC | Published : 2018
Abstract
Purpose: To develop consensus terminology and criteria for defining atrophy based on OCT findings in the setting of age-related macular degeneration (AMD). Design: Consensus meeting. Participants: Panel of retina specialists, image reading center experts, retinal histologists, and optics engineers. Methods: As part of the Classification of Atrophy Meetings (CAM) program, an international group of experts surveyed the existing literature, performed a masked analysis of longitudinal multimodal imaging for a series of eyes with AMD, and reviewed the results of this analysis to define areas of agreement and disagreement. Through consensus discussions at 3 meetings over 12 months, a classificatio..
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Awarded by National Eye Institute
Funding Acknowledgements
The author(s) have made the following disclosure(s): S.R.S.: Consultant - Allergan, Iconic Therapeutics, Novartis, Thrombogenics, Genentech, Centervue, Heidelberg Engineering; Research support - Optos, Carl Zeiss Meditec, Allergan; Research Instruments - Optos, Carl Zeiss Meditec, Nidek, Centervue, Heidelberg Engineering R.G.: Financial support - Novartis, Bayer, Genentech F.G.H.: Financial support - Heidelberg Engineering, Optos, Zeiss, Novartis, Bayer Healthcare, Genentech, Acucela, Boehringer Ingelheim, Alcon, Allergan S.S.-V.: Financial support - Novartis, Bayer Healthcare, Genentech, Acucela, Alcon, Allergan, Heidelberg Engineering, Formycon/Bioeq; Nonfinancial support - Optos, Heidelberg Engineering, Carl Zeiss Meditec C.A.C.: Financial support - Hoffman-LaRoche, Heidelberg Engineering, Regeneron, Novartis, Unity, Janssen Cell Therapy K.C.: Financial support - Genentech, Regeneron, Heidelberg Engineering, Santen, Ophthotech, Acucela, GSK, Roche, Allergan; Other - Ophthotech R.D.: Financial support - Allergan, GSK, Thrombogenics, KangHong, Ionis; Equity owner - EyeKor, Inc; Employee - EyeKor, Inc K.B.F.: Consultant - Heidelberg Engineering, Optovue, Optos, Spark Therapeutics; Financial support - Genentech/Roche J.M.M.: Financial support - Eyerisk Consortium 2020, Novartis, Bayer, Alcon, Roche, Ophthotech; Consultant - Novartis, Bayer, Alcon, Roche, Genentech; Equity owner - Ophthotech, Notalvision P.J.R.: Research support - Astellas Institute for Regenerative Medicine (AIRM), Carl Zeiss Meditec, Genentech, Tyrogenex; Consultant - Acucela, Apellis, Boehringer-Ingelheim, Carl Zeiss Meditec, Cell Cure Neurosciences, Chengdu Kanghong Biotech, Isarna Therapeutics, Genentech, Healios K.K., Hemera Biosciences, F. Hoffmann-La Roche Ltd., Ocudyne, Ocunexus, Tyrogenex, Unity Biotechnology; Equity Interest - Apellis, Digisight, Ocudyne D.S.: Consultant - Genentech, Optovue, Bayer, Novartis; Financial support - Allergan, Genentech, Heidelberg Engineering, Regeneron, Optovue, Optovue; Lecturer - Optovue R.T.: Financial support - Alcon, Allergan, Alimera, Novartis, Bayer, B+L, FCI, Zeiss, Thromgenics, Genentech, Roche; Nonfinancial support - Alcon, Allergan, Novartis, Bayer, B+L, Zeiss G.S.: Financial support - Heidelberg Engineering, Zeiss Meditec, Optovue, Optos, Centervue, Nidek, Novartis, Bayer; Other - Heidelberg Engineering, Zeiss Meditec, Optos, Centervue, Novartis, Bayer, Boeheringer, Allergan, Alcon Acquisition of human donor eyes and the Project MACULA web site were supported by the National Institutes of Health, Bethesda, Maryland (grant nos.: R01EY06019 and P30 EY003039 [C.A.C.]); EyeSight Foundation of Alabama (C.A.C.); International Retinal Research Foundation (C.A.C.); the Edward N. and Della L. Thome Foundation (C.A.C.); the Arnold and Mabel Beckman Initiative for Macular Research (C.A.C.); and Research to Prevent Blindness, Inc, New York, New York (C.A.C.). Supported by the Lowy Research Medical Institute (travel grant, A.C.B.).