Journal article

A structural motor network correlates with motor function and not impairment post stroke

Sue Peters, Katie P Wadden, Kathryn S Hayward, Jason L Neva, Angela M Auriat, Lara A Boyd

NEUROSCIENCE LETTERS | ELSEVIER IRELAND LTD | Published : 2017

Abstract

Combining structural and functional magnetic resonance imaging may provide insight into how residual motor networks contribute to motor outcomes post-stroke. The purpose of this study was to examine whether a structural motor network (SMN), generated with fMRI guided diffusion-based tractography, relates to motor function post-stroke. Twenty-seven individuals with mild to moderate upper limb impairment post stroke underwent diffusion magnetic resonance imaging. A bilateral motor network mask guided white matter tractography for each participant. Fractional anisotrophy (FA) was calculated for the SMN and corticospinal tracts (CST). The Wolf Motor Function Test (WMFT) rate and Fugl-Meyer Upper..

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University of Melbourne Researchers

Grants

Awarded by Canadian Institutes of Health Research


Awarded by Michael Smith Foundation for Health Research


Awarded by National Health and Medical Research Council of Australia


Funding Acknowledgements

Funding for this work was provided by the Canadian Institutes of Health Research (PI Boyd, MOP-106651) and the Centre for Progress in Stroke Recovery/Heart and Stroke Foundation of Canada (PI Boyd). SP received support from the Canadian Institutes of Health Research and the IODE War Memorial Scholarship; Natural Sciences and Engineering Council of Canada provided support to KPW; KSH receives supports from the Heart and Stroke Foundation of Canada, Michael Smith Foundation for Health Research (15980), and the National Health and Medical Research Council of Australia (1088449); JLN receives salary support from the Canadian Institutes of Health Research and the Michael Smith Foundation for Health Research; AA receives support from Michael Smith Foundation for Health Research and the Canadian Partnership for Stroke Recovery.