Book Chapter
Transplant dermatology clinics
AH Chong, C Holmes
Skin Disease in Organ Transplantation | Published : 2008
Abstract
INTRODUCTION. As the number of living organ transplant recipients continues to rise with advances in immunosuppression, so do the long-term problems. Nonmelanoma skin cancers (NMSCs), particularly squamous cell carcinomas (SCCs) are the most common posttransplantation malignancy in countries with predominantly Caucasian populations. In subtropical Queensland, Australia, the cumulative incidence of NMSCs increased from 7% after one year of immunosuppression to 25% after 5 years, and 70% after 20 years. The mean NMSC accrual in this same population was calculated as 1.85 +/− 3.84 tumors /person/year, increasing to 3.35 +/− 4.29 tumors/person/year after 20 years of immunosuppressive therapy, re..
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