Food Allergy Is an Important Risk Factor for Childhood Asthma, Irrespective of Whether It Resolves

EM Vermeulen; JJ Koplin; SC Dharmage; LC Gurrin; RL Peters; V McWilliam; AL Ponsonby; T Dwyer; AJ Lowe; MLK Tang; KJ Allen; M Wake; M Matheson; C Robertson; D Hill

Journal article

Food Allergy Is an Important Risk Factor for Childhood Asthma, Irrespective of Whether It Resolves

EM Vermeulen, JJ Koplin, SC Dharmage, LC Gurrin, RL Peters, V McWilliam, AL Ponsonby, T Dwyer, AJ Lowe, MLK Tang, KJ Allen, M Wake, M Matheson, C Robertson, D Hill

Journal of Allergy and Clinical Immunology in Practice | ELSEVIER SCIENCE BV | Published : 2018

DOI: 10.1016/j.jaip.2017.10.019

Abstract

Background: The risk of developing asthma in those with early food allergy is unknown, particularly when early life food allergy has resolved. Objective: To understand whether challenge-proven food allergy in infancy increases the risk of asthma at age 4 years, using data from a population-based cohort. Methods: A total of 5,276 12-month-old infants were recruited using a population-based sampling frame. Infants underwent skin prick test to egg, peanut, and sesame and those with a detectable skin prick test result had oral food challenges. At age 4 years, food challenges were repeated to determine persistence or resolution of food allergy. The association between food allergy and doctor-diag..

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University of Melbourne Researchers

Shyamali Dharmage Author

Lyle Gurrin Author

Rachel Peters Author

Anne-Louise Ponsonby Author

Grants

Funding Acknowledgements

This work was supported by funding from the National Health & Medical Research Council (NHMRC) of Australia, Ilhan Food Allergy Foundation, AnaphylaxiStop, the Charles and Sylvia Viertel Medical Research Foundation, the Victorian Government's Operational Infrastructure Support Program, and the NHMRC Centre for Food and Allergy Research. K. A., L. C. G., A. J. L., A.-L. P., and S. C. D. hold NHMRC awards.