EFFECTS OF STIMULATION ON THE MULTIQUANTAL SPONTANEOUS SYNAPTIC POTENTIALS IN GUINEA-PIG HYPOGASTRIC GANGLIA
NEUROSCIENCE LETTERS | ELSEVIER SCI IRELAND LTD | Published : 1981
Loss frequency (0.5-2 Hz) stimulation of the preganglionic nerve produced calcium ion (Ca2+)-dependent increases in the frequency of spontaneous synaptic potentials recorded from guinea-pig hypogastric ganglion cells. The increased frequency was accompanied by a marked increase in the proportion of multiquantal spontaneous potentials and this was also dependent on extracellular Ca2+. The latter effect was interpreted as an increase in the degree of bursting within the spontaneous release process, supporting the hypothesis that the bursting is related to the cytoplasmic Ca2+ concentration.