Journal article
Propensity score matched analysis of partial atrioventricular septal defect repair in infancy
E Buratto, M Daley, XT Ye, DJ Radford, N Alphonso, CP Brizard, Y D'Udekem, IE Konstantinov
Heart | BMJ PUBLISHING GROUP | Published : 2018
Abstract
Objective Partial atrioventricular septal defect (pAVSD) is usually repaired between 2 and 4 years of age with excellent results. Repair during infancy has been associated with poorer outcomes. However, most infants in reported series had heart failure or significant left atrioventricular valve (LAVV) regurgitation. The impact of surgery during infancy on outcomes remains unclear. Methods A ll children at three institutions who underwent repair of pAVSD from 1975 to 2015 were included. Infants (aged <1 year) were compared with older children in a propensity score matched analysis. Variables used to generate propensity scores were: failure to thrive, congestive heart failure, preoperative LAV..
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Awarded by National Health and Medical Research Council
Funding Acknowledgements
This project was supported by the Victoria Government's Operational Infrastructure Support Program. EB is a recipient of a Reg Worcester Scholarship from the Royal Australasian College of Surgeons. Yd'U is a National Health and Medical Research Council Clinician Practitioner Fellow (1082186).