Journal article

A virtual dosimetry audit - Towards transferability of gamma index analysis between clinical trial QA groups

Mohammad Hussein, Enrico Clementel, David J Eaton, Peter B Greer, Annette Haworth, Satoshi Ishikura, Stephen F Kry, Joerg Lehmann, Jessica Lye, Angelo F Monti, Mitsuhiro Nakamura, Coen Hurkmans, Catharine H Clark

RADIOTHERAPY AND ONCOLOGY | ELSEVIER IRELAND LTD | Published : 2017

Abstract

PURPOSE: Quality assurance (QA) for clinical trials is important. Lack of compliance can affect trial outcome. Clinical trial QA groups have different methods of dose distribution verification and analysis, all with the ultimate aim of ensuring trial compliance. The aim of this study was to gain a better understanding of different processes to inform future dosimetry audit reciprocity. MATERIALS: Six clinical trial QA groups participated. Intensity modulated treatment plans were generated for three different cases. A range of 17 virtual 'measurements' were generated by introducing a variety of simulated perturbations (such as MLC position deviations, dose differences, gantry rotation errors,..

View full abstract

University of Melbourne Researchers