Journal article

Relationship between caries experience and demarcated hypomineralised lesions (including MIH) in the permanent dentition of 15-year-olds

Jan Kuehnisch, Lamiaa Kabary, Yuri Malyk, Katrin Rothmaier, Isabel Metz, Reinhard Hickel, Joachim Heinrich, David Manton, Marie Standl

CLINICAL ORAL INVESTIGATIONS | SPRINGER HEIDELBERG | Published : 2018

Abstract

OBJECTIVE: This cross-sectional study compared the caries experience in 15-year-olds with and without demarcated hypomineralised lesions (DHL) in permanent teeth. MATERIAL AND METHODS: One thousand three hundred and two 15-year-old adolescents from two ongoing birth cohorts (GINIplus15 and LISAplus15) were examined to determine non-cavitated carious lesions (NCCL) and the DMF index. Furthermore, DHL was scored on all permanent teeth/surfaces according to the molar-incisor hypomineralisation criteria of the European Academy of Paediatric Dentistry (MIH/EAPD). Adolescents with DHL were categorised into those with a minimum of one DHL in the permanent dentition (DHL ≥ 1), with DHL on at least o..

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University of Melbourne Researchers

Grants

Awarded by Federal Ministry for Environment (IUF Dusseldorf)


Awarded by German Research Foundation (Deutsche Forschungsgemeinschaft)


Funding Acknowledgements

The GINIplus study was mainly supported for the first 3 years of the Federal Ministry for Education, Science, Research and Technology (interventional arm) and Helmholtz Zentrum Munich (former GSF) (observational arm). The 4-, 6-, 10- and 15-year follow-up examinations of the GINIplus study were covered from the respective budgets of the five study centres (Helmholtz Zentrum Munich (former GSF), Research Institute at Marien- Hospital Wesel, LMU Munich, TU Munich and from 6 years onwards also from IUF - Leibniz Research-Institute for Environmental Medicine at the University of Dusseldorf) and a grant from the Federal Ministry for Environment (IUF Dusseldorf, FKZ 20462296). The LISAplus study was mainly supported by grants from the Federal Ministry for Education, Science, Research and Technology and in addition from Helmholtz Zentrum Munich (former GSF), Helmholtz Centre for Environmental Research - UFZ, Leipzig, Research Institute at Marien- Hospital Wesel, Pediatric Practice, Bad Honnef for the first 2 years. The 4-, 6-, 10- and 15-year follow-up examinations of the LISAplus study were covered from the respective budgets of the involved partners (Helmholtz Zentrum Munich (former GSF), Helmholtz Centre for Environmental Research - UFZ, Leipzig, Research Institute at Marien- Hospital Wesel, Pediatric Practice, Bad Honnef, IUF - Leibniz-Research Institute for Environmental Medicine at the University of Dusseldorf) and in addition by a grant from the Federal Ministry for Environment (IUF Dusseldorf, FKZ 20462296). Further, the 15-year follow-up examination of the GINIplus and LISAplus studies was supported by the Commission of the European Communities, the 7th Framework Program: MeDALL project. The 15-year follow-up examination of the GINIplus study was additionally supported by the Mead Johnson and Nestle companies. The dental investigation was funded by grants obtained from the German Research Foundation (Deutsche Forschungsgemeinschaft, FKZ KU-2518/1-1, KU-2518/1-2, HE-3294/7-1 and HE-3294/7-2). The GABA GmbH, Lorrach, Germany, supported this study by providing oral health care packages for all of the participating children as incentives.