Changing epidemiology of type 2 diabetes mellitus and associated chronic kidney disease
Merlin C Thomas, Mark E Cooper, Paul Zimmet
NATURE REVIEWS NEPHROLOGY | NATURE PUBLISHING GROUP | Published : 2016
Chronic kidney disease (CKD) is a common comorbidity in patients with type 2 diabetes mellitus (T2DM) and both conditions are increasing in prevalence. CKD is estimated to affect ∼50% patients with T2DM globally, and its presence and severity markedly influences disease prognosis. CKD is more common in certain patient populations, including the elderly, those with youth-onset diabetes mellitus, those who are obese, certain ethnic groups, and disadvantaged populations. These same settings have also seen the greatest increase in the prevalence of T2DM, as exemplified by the increasing prevalence of T2DM in low-to- middle income countries. Patients from low-to-middle income countries are often ..View full abstract
M.C.T. and M.E.C. are supported by NHMRC research fellowships. The Baker IDI is supported by infrastructure funding from the Victorian government, Australia.