Journal article

Noninvasive Cardiac Imaging and the Prediction of Heart Failure Progression in Preclinical Stage A/B Subjects

Fei Fei Gong, Duncan J Campbell, David L Prior



Heart failure (HF) continues to grow as a cause of morbidity and mortality in our community and presents a significant public health problem, predominantly in individuals ≥65 years of age. Early intervention in asymptomatic HF subjects (Stage A/B) at risk of progression to symptomatic HF (Stage C/D) may provide an opportunity to halt this epidemic. The ability of cardiac imaging to assess cardiac structure and function permits early identification of those at increased risk of developing symptomatic HF. Systolic, diastolic, and structural left ventricular parameters each predict symptomatic HF, but no single parameter has sufficient sensitivity for screening to identify individuals with Stag..

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Funding Acknowledgements

From the <SUP>a</SUP>Department of Medicine, University of Melbourne, St. Vincent's Hospital Melbourne, Fitzroy, Australia; <SUP>b</SUP>St. Vincent's Institute of Medical Research, Fitzroy, Australia; and the <SUP>c</SUP>Department of Cardiology, St. Vincent's Hospital Melbourne, Fitzroy Australia. St. Vincent's Institute of Medical Research is supported in part by the Victorian Government's Operational Infrastructure Support Program. The authors have reported that they have no relationships relevant to the contents of this paper to disclose.