Journal article
Interhemispheric Pathways Are Important for Motor Outcome in Individuals with Chronic and Severe Upper Limb Impairment Post Stroke
KS Hayward, JL Neva, CS Mang, S Peters, KP Wadden, JK Ferris, LA Boyd
Neural Plasticity | HINDAWI LTD | Published : 2017
DOI: 10.1155/2017/4281532
Abstract
Background. Severity of arm impairment alone does not explain motor outcomes in people with severe impairment post stroke. Objective. Define the contribution of brain biomarkers to upper limb motor outcomes in people with severe arm impairment post stroke. Methods. Paretic arm impairment (Fugl-Meyer upper limb, FM-UL) and function (Wolf Motor Function Test rate, WMFT-rate) were measured in 15 individuals with severe (FM-UL ≤ 30/66) and 14 with mild-moderate (FM-UL > 40/66) impairment. Transcranial magnetic stimulation and diffusion weight imaging indexed structure and function of the corticospinal tract and corpus callosum. Separate models of the relationship between possible biomarkers and ..
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Awarded by Michael Smith Foundation for Health Research
Funding Acknowledgements
This work was funded by a grant from the Canadian Institutes of Health Research (CIHR) (MOP-106651 to Lara A. Boyd). Kathryn S. Hayward was supported by the Heart and Stroke Foundation Canada, Michael Smith Foundation for Health Research (MSFHR), British Columbia, Canada (15980), and National Health and Medical Research Council of Australia (1088449); Jason L. Neva was supported by CIHR and MSFHR; Cameron S. Mang and Katie P. Wadden were supported by Natural Sciences and Engineering Research Council; Sue Peters and Jennifer K. Ferris were supported by CIHR; and Lara A. Boyd was supported by the Canada Research Chairs and the MSFHR (CI-SCH-01796).