Haploinsufficiency for the Six2 gene increases nephron progenitor proliferation promoting branching and nephron number
Alexander N Combes, Sean Wilson, Belinda Phipson, Brandon B Binnie, Adler Ju, Kynan T Lawlor, Cristina Cebrian, Sarah L Walton, Ian M Smyth, Karen M Moritz, Raphael Kopan, Alicia Oshlack, Melissa H Little
Kidney International | ELSEVIER SCIENCE INC | Published : 2018
Awarded by Australian Research Council
Awarded by National Health and Medical Research Council of Australia
Awarded by Human Frontiers in Science Program
This work was supported by the Australian Research Council (DE150100652), the National Health and Medical Research Council of Australia (APP1002748, APP1063696), the Human Frontiers in Science Program (RGP0039/2011). Microscopy was performed at the ACRF/IMB Cancer Biology Imaging Facility at Monash University and the Murdoch Children's Research Institute. ANC holds a Discovery Early Career Researcher Award from the Australian Research Council. MHL is a Senior Principal Research Fellow of the NHMRC. We thank the IMB Sequencing Facility for NGS services, David Ornitz for the Fgf20 mice, Kieran Short, Lynelle Jones, Shireen Lamande, Chantal Coles, and Peter Houweling for technical assistance. MCRI is supported by the Victorian Government's Operational Infrastructure Support Program.