Journal article

CORRELATION OF DIRECTLY OBSERVED RESPONSES OF MESENTERIC VESSELS OF RAT TO NERVE-STIMULATION AND NORADRENALINE WITH DISTRIBUTION OF ADRENERGIC NERVES

JB FURNESS, JM MARSHALL

JOURNAL OF PHYSIOLOGY-LONDON | CAMBRIDGE UNIV PRESS | Published : 1974

Abstract

1. The effects of nerve stimulation and of the topical application of noradrenaline on arteries, capillaries and veins of the mesentery of the anaesthetized rat were examined by direct observation under a microscope. The distribution of adrenergic nerves to the vessels of the mesentery was studied using the fluorescence histochemical method.2. Principal arteries, small arteries and terminal arterioles were all innervated by a network of adrenergic fibres and they all constricted in response to the stimulation of paravascular nerves and to exogenous noradrenaline. Few adrenergic fibres accompanied the smaller, precapillary arterioles; these vessels did not respond to nerve stimulation, althou..

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