The Prevalence of Food Sensitization Appears Not to Have Changed between 2 Melbourne Cohorts of High-Risk Infants Recruited 15 Years Apart

RL Peters; JJ Koplin; KJ Allen; AJ Lowe; CJ Lodge; MLK Tang; M Wake; AL Ponsonby; B Erbas; MJ Abramson; D Hill; LC Gurrin; SC Dharmage

Journal article

The Prevalence of Food Sensitization Appears Not to Have Changed between 2 Melbourne Cohorts of High-Risk Infants Recruited 15 Years Apart

RL Peters, JJ Koplin, KJ Allen, AJ Lowe, CJ Lodge, MLK Tang, M Wake, AL Ponsonby, B Erbas, MJ Abramson, D Hill, LC Gurrin, SC Dharmage

Journal of Allergy and Clinical Immunology in Practice | ELSEVIER SCIENCE BV | Published : 2018

DOI: 10.1016/j.jaip.2017.11.018

Abstract

Background: Although food allergy has probably risen over recent decades, recent reports suggest that the prevalence of food sensitization in the general population has not changed. However, this has not been analyzed in infants at high risk of food allergy. Objective: The objective of this study was to compare the prevalence of food sensitization in high-risk infants from 2 cohorts recruited 15 years apart in the same region. Methods: This study includes 620 high-risk infants with a family history of allergy (Melbourne Atopy Cohort Study [MACS]) born 1990-1994, and a subgroup of high-risk infants from the population-based HealthNuts study (n = 3,661/5,276), born 2006-2010. Both studies unde..

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University of Melbourne Researchers

Rachel Peters Author

Adrian Lowe Author

Caroline Lodge Author

Mimi Tang Author

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Funding Acknowledgements

The HealthNuts study was supported by funding from the National Health & Medical Research Council (NHMRC) of Australia, Ilhan Food Allergy Foundation, AnaphylaxiStop, the Charles and Sylvia Viertel Medical Research Foundation, the Victorian Government's Operational Infrastructure Support Program, and the NHMRC Centre for Food and Allergy Research. K. J. Allen, L. C. Gurrin, A. J. Lowe, J. J. Koplin, and S. C. Dharmage hold NHMRC awards. M. Wake was supported by an NHMRC award and Cure Kids New Zealand. The first 6 years of the Melbourne Atopy Cohort Study (MACS) was funded (study formula and staff) by Nestec Ltd, a subsidiary of Nestle Australia. The 12-year follow-up was supported by Victorian Asthma Foundation and 18-year and 25-year follow-ups have been funded by NHMRC. All bodies that have funded aspects of the MACS have had no role in interpretation or publication of study findings.