Relationship between reticular pseudodrusen and choroidal thickness in intermediate age-related macular degeneration

Abstract

Importance: Reticular pseudodrusen (RPD) is strongly associated with late age-related macular degeneration (AMD) but their aetiology remains unknown. RPD have been associated with reduced choroidal thickness (ChT) but most studies are limited by small sample size and varying severity of AMD. Background: To investigate the relationship between choroidal thickness and RPD in eyes with intermediate AMD (iAMD), controlling for variables known to influence ChT. Design: Retrospective cohort study. Participants: Participants were recruited from Centre for Eye Research Australia. Methods: Colour fundus photographs, fundus auto fluorescence, near-infrared and spectral-domain ocular coherence tomograp..