Health economic implications of complications associated with pancreaticoduodenectomy at a University Hospital: a retrospective cohort cost study

Abstract

Background: A cost analyses of complications following pancreaticoduodenectomy (PD) was performed in a high volume hepato-biliary-pancreatic service. We hypothesised that costs are increased with both severity and number of complications; we investigated the relationship between complications and specific cost centres. Methods: 100 patients from 2011 to 2016 were included. Data relating to their perioperative course were collected. Complications were documented by the Clavien–Dindo classification and costs were inflated and converted to 2017 USD. Results: Mean hospital costs in complicated patients more than doubled those of uncomplicated patients ($28 330 vs. $57 150, p < 0.0001). T..