Journal article

Can CT perfusion accurately assess infarct core?

Dan C Huynh, Mark W Parsons, Max Wintermark, Achala Vagal, Christopher D d’Esterre, Rita Vitorino, Daniel Efkehari, Jesse Knight, Thien J Huynh, Andrew Bivard, Rick Swartz, Sean Symons, Richard I Aviv

Neurovascular Imaging | Springer Science and Business Media LLC | Published : 2016

DOI: 10.1186/s40809-016-0018-1

Abstract

BackgroundWe sought to quantify CTP-derived infarct core applying previously published perfusion thresholds to multi-institutional CTP data to assess the margin of error for 25 mL and 70 mL critical volume thresholds using early DWI as a reference standard.Methods60 patients with acute ischemic stroke undergoing CTP and DWI within 6 and 24 h of symptom onset, respectively, were retrospectively analyzed from 3 tertiary care centers. CTP-derived infarct core was calculated using published thresholds for absolute and relative CBF and CBV in addition to manual CBV tracing. Using DWI as the reference standard, performance of CTP-derived measures of infarct core was assessed using co-registered vo..

View full abstract

University of Melbourne Researchers

Grants

Awarded by Imaging Core Lab, PRISMS Trial, Genentech, Inc.

Citation metrics

9Dimensions

Keywords

Stroke
Cerebrovascular
3202 Clinical Sciences
32 Biomedical and Clinical Sciences
Brain Disorders
Clinical Research