Journal article

Diabetic retinopathy and macular edema quality-of-life item banks: Development and initial evaluation using computerized adaptive testing

EK Fenwick, J Khadka, K Pesudovs, G Rees, TY Wong, EL Lamoureux

Investigative Ophthalmology and Visual Science | ASSOC RESEARCH VISION OPHTHALMOLOGY INC | Published : 2017

Open access

Abstract

PURPOSE. The purpose of this study was to assess the psychometric properties of diabetic retinopathy (DR) and diabetic macular edema (DME) quality-of-life (QoL) item banks and determine the utility of the final calibrated item banks by simulating a computerized adaptive testing (CAT) application. METHODS. In this clinical, cross-sectional study, 514 participants with DR/DME (mean age ± SD, 60.4 ± 12.6 years; 64% male) answered 314 items grouped under nine QoL item pools: Visual Symptoms (SY); Ocular Comfort Symptoms (OS); Activity Limitation (AL); Mobility (MB); Emotional (EM); Health Concerns (HC); Social (SC); Convenience (CV); and Economic (EC). The psychometric properties of the item poo..

View full abstract

University of Melbourne Researchers

Grants

Awarded by National Health and Medical Research Council


Funding Acknowledgements

Supported by National Health and Medical Research Council Centre for Clinical Research Excellence (CCRE) Grant 529923 (Translational Clinical Research in Major Eye Diseases); CCRE Diabetes; Novartis Pharmaceuticals Australia Grant CRFB002DAU09T; and the Royal Victorian Eye and Ear Hospital. EKF is funded by Australian National Health and Medical Research Council (NHMRC) Early Career Fellowship 1072987. GR is funded by NHMRC Career Development Award 1061801 The Centre for Eye Research Australia receives Operational Infrastructure Support from the Victorian Government.