Journal article
A Nonpeptidic Cathepsin S Activity-Based Probe for Noninvasive Optical Imaging of Tumor-Associated Macrophages
Martijn Verdoes, Laura E Edgington, Ferenc A Scheeren, Melissa Leyva, Galia Blum, Kipp Weiskopf, Michael H Bachmann, Jonathan A Ellman, Matthew Bogyo
Chemistry & Biology | CELL PRESS | Published : 2012
Grants
Awarded by National Institutes of Health
Awarded by NATIONAL CANCER INSTITUTE
Awarded by NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
Awarded by NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING
Awarded by NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
Funding Acknowledgements
We thank J. Lee for help with synthesis, A. W. Pun for assistance with macrophage isolation, and M. A. Child and E. Due for critical discussions. We also thank T. Doyle at the Stanford Small Animal Facility at Stanford for assistance with optical imaging studies and S. R. Lynch at the Stanford University Department of Chemistry NMR facility for assistance. This work was supported by the National Institutes of Health (grants R01 EB005011 and R01 AI078947 to M.B.). M.V. is supported by a Rubicon fellowship from the Netherlands Organization for Scientific Research (NWO).