Journal article

Wavelet feature extraction and genetic algorithm for biomarker detection in colorectal cancer data

Yihui Liu, Uwe Aickelin, Jan Feyereisl, Lindy G Durrant

Knowledge-Based Systems | Elsevier | Published : 2013


Biomarkers which predict patient’s survival play an important role in medical diagnosis and treatment. How to select the significant biomarkers from hundreds of protein markers is a key step in survival analysis. In this paper a novel method is proposed to detect the prognostic biomarkers of survival in colorectal cancer patients using wavelet analysis, genetic algorithm, and Bayes classifier. One dimensional discrete wavelet transform (DWT) is normally used to reduce the dimensionality of biomedical data. In this study one dimensional continuous wavelet transform (CWT) was proposed to extract the features of colorectal cancer data. One dimensional CWT has no ability to reduce dimensionality..

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University of Melbourne Researchers