Tailored RF Pulse for Magnetization Inversion at Ultrahigh Field

Abstract

The radiofrequency (RF) transmit field is severely inhomogeneous at ultrahigh field due to both RF penetration and RF coil design issues. This particularly impairs image quality for sequences that use inversion pulses such as magnetization prepared rapid acquisition gradient echo and limits the use of quantitative arterial spin labeling sequences such as flow-attenuated inversion recovery. Here we have used a search algorithm to produce inversion pulses tailored to take into account the heterogeneity of the RF transmit field at 7 T. This created a slice selective inversion pulse that worked well (good slice profile and uniform inversion) over the range of RF amplitudes typically obtained in ..