Histiocytic sarcoma in 14 miniature schnauzers – a new breed predisposition?

Abstract

Objectives: To describe a series of miniature schnauzers diagnosed with histiocytic sarcoma and assess for possible breed predisposition. Materials and Methods: Medical records of miniature schnauzers with a diagnosis of histiocytic sarcoma between January 2008 and April 2015 were reviewed. Data collected included signalment, body weight, presenting complaint, date of diagnosis, clinicopathologic and diagnostic imaging findings, treatment, therapeutic response, date of death or last follow-up and necropsy findings. Breed predisposition was assessed with odds ratios, using breed-matched dogs without histiocytic sarcoma admitted during the study period as controls. Pedigree analysis was perfor..