Engineering of plants with improved properties as biofuels feedstocks by vessel-specific complementation of xylan biosynthesis mutants
Pia Damm Petersen, Jane Lau, Berit Ebert, Fan Yang, Yves Verhertbruggen, Jin Sun Kim, Patanjali Varanasi, Anongpat Suttangkakul, Manfred Auer, Dominique Loque, Henrik Vibe Scheller
Biotechnology for Biofuels | BIOMED CENTRAL LTD | Published : 2012
UNLABELLED: BACKGROUND: Cost-efficient generation of second-generation biofuels requires plant biomass that can easily be degraded into sugars and further fermented into fuels. However, lignocellulosic biomass is inherently recalcitrant toward deconstruction technologies due to the abundant lignin and cross-linked hemicelluloses. Furthermore, lignocellulosic biomass has a high content of pentoses, which are more difficult to ferment into fuels than hexoses. Engineered plants with decreased amounts of xylan in their secondary walls have the potential to render plant biomass a more desirable feedstock for biofuel production. RESULTS: Xylan is the major non-cellulosic polysaccharide in seconda..View full abstract
Awarded by US Department of Energy, Office of Science, Office of Biological and Environmental Research
This work was funded by the US Department of Energy, Office of Science, Office of Biological and Environmental Research, through contract DE-AC02-05CH11231 with Lawrence Berkeley National Laboratory. PDP was additionally supported by: Augustinus Fonden, Direktor Ib Henriksens Fond, Fabrikant Vilhelm Pedersen og Hustrus Legat, Faellesfonden for Soren Christian Sorensen og Hustrus Mindefond og Foreningen af Jydske Landboforeninger, Henry & Mary Skovs Fond, Hotelejer Anders Mansson og Hustrus Legat, HP Olsen og Hustrus Mindefond, Knud Hojgaards Fond, KVLs Jubilaeumsfond, Landlegatet and Oticon Fonden. Dr. Daniel Klein-Marcuschamer is thanked for assistance with determining potential economic impact of the engineering strategy, and Dr. Prajakta Mitra for help with lignin determination.