Journal article
No association between ACTN3 R577X and ACE I/D polymorphisms and endurance running times in 698 Caucasian athletes
ID Papadimitriou, SJ Lockey, S Voisin, AJ Herbert, F Garton, PJ Houweling, P Cieszczyk, A Maciejewska-Skrendo, M Sawczuk, M Massidda, CM Calò, IV Astratenkova, A Kouvatsi, AM Druzhevskaya, M Jacques, II Ahmetov, GK Stebbings, S Heffernan, SH Day, R Erskine Show all
BMC Genomics | BMC | Published : 2018
Open access
Abstract
Background: Studies investigating associations between ACTN3 R577X and ACE I/D genotypes and endurance athletic status have been limited by small sample sizes from mixed sport disciplines and lack quantitative measures of performance. Aim: To examine the association between ACTN3 R577X and ACE I/D genotypes and best personal running times in a large homogeneous cohort of endurance runners. Methods: We collected a total of 1064 personal best 1500, 3000, 5000 m and marathon running times of 698 male and female Caucasian endurance athletes from six countries (Australia, Greece, Italy, Poland, Russia and UK). Athletes were genotyped for ACTN3 R577X and ACE ID variants. Results: There was no asso..
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