Criteria for Identifying Patients With Staphylococcus aureus Bacteremia Who Are at Low Risk of Endocarditis: A Systematic Review
George S Heriot, Katie Cronin, Steven YC Tong, Allen C Cheng, Danny Liew
Open Forum Infectious Diseases | OXFORD UNIV PRESS INC | Published : 2017
This systematic review examines the methods and results of recent studies reporting clinical criteria able to identify patients with Staphylococcus aureus bacteremia who are at very low risk of endocarditis. We searched PubMed, EMBASE, and the Cochrane Collaboration CENTRAL database for articles published after March 1994 using a combination of MeSH and free text search terms for S. aureus AND bacteremia AND endocarditis. Studies were included if they presented a combination of clinical and microbiological criteria with a negative likelihood ratio of ≤0.20 for endocarditis. We found 8 studies employing various criteria and reference standards whose criteria were associated with negative like..View full abstract
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G.S.H. is supported by the Australian Government Research Training Program and a Monash University Faculty of Medicine, Nursing and Health Sciences postgraduate excellence award. S.Y.C.T. is an Australian National Health and Medical Research Council Career Development Fellow (#1065736).