Journal article

Field effectiveness of highly pathogenic avian influenza H5N1 vaccination in commercial layers in Indonesia

Simson Tarigan, Michael Haryadi Wibowo, Risa Indriani, Sumarningsih Sumarningsih, Sidna Artanto, Syafrison Idris, Peter A Durr, Widya Asmara, Esmaeil Ebrahimie, Mark A Stevenson, Jagoda Ignjatovic

PLOS ONE | PUBLIC LIBRARY SCIENCE | Published : 2018

Abstract

Although vaccination of poultry for control of highly pathogenic avian influenza virus (HPAIV) H5N1 has been practiced during the last decade in several countries, its effectiveness under field conditions remains largely unquantified. Effective HPAI vaccination is however essential in preventing incursions, silent infections and generation of new H5N1 antigenic variants. The objective of this study was to asses the level and duration of vaccine induced immunity in commercial layers in Indonesia. Titres of H5N1 haemagglutination inhibition (HI) antibodies were followed in individual birds from sixteen flocks, age 18-68 week old (wo). The study revealed that H5N1 vaccination had highly variabl..

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University of Melbourne Researchers

Grants

Awarded by Australian Center for International Agricultural Research (ACIAR)


Funding Acknowledgements

Financial support was provided by Australian Center for International Agricultural Research (ACIAR), WWW.aciar.gov.au, Grant No: AH2010/039, Author received the funding: JI. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.