Journal article

Aripiprazole (intramuscular) for psychosis-induced aggression or agitation (rapid tranquillisation)

Edoardo G Ostinelli, Salwan Jajawi, Styliani Spyridi, Kamlaj Sayal, Mahesh B Jayaram

Cochrane Database of Systematic Reviews | WILEY | Published : 2018


BACKGROUND: People experiencing psychosis may become aggressive. Antipsychotics, such as aripiprazole in intramuscular form, can be used in such situations. OBJECTIVES: To evaluate the effects of intramuscular aripiprazole in the treatment of psychosis-induced aggression or agitation (rapid tranquillisation). SEARCH METHODS: On 11 December 2014 and 11 April 2017, we searched the Cochrane Schizophrenia Group's Study-based Register of Trials which is based on regular searches of CINAHL, BIOSIS, AMED, Embase, PubMed, MEDLINE, PsycINFO, and registries of clinical trials. SELECTION CRITERIA: All randomised controlled trials (RCTs) that randomised people with psychosis-induced aggression or agitat..

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University of Melbourne Researchers


Funding Acknowledgements

Internal sourcesUniversita degli Studi di Milano, Milan, Italy. Employs lead author Edoardo G Ostinelli.Rotherham, Doncaster and South Humber NHS Foundation Trust, Rotherham, UK. Employs review author Salwan Jajawi.Cyprus University of Technology, Lemesos, Cyprus. Employs review author Styliani Spyridi.UK LLP, Dewsbury, UK. Employs review author Styliani Spyridi.Cygnet Hospital Derby, UK. Employs review author Kamlaj Sayal.Melbourne Neuropsychiatry Centre, Melbourne, Australia. Employs review author Mahesh B Jayaram.