Journal article

CIRCULATING MUCINS AS TUMOR-MARKERS IN OVARIAN-CANCER

PL DEVINE, MA MCGUCKIN, BG WARD

ANTICANCER RESEARCH | INT INST ANTICANCER RESEARCH | Published : 1992

Abstract

Because a highly sensitive and specific serum marker for ovarian carcinoma has not been reported, it is unlikely that there will be an application of serum markers for screening for this disease in asymptomatic women. However, many oncologists use serum tumor markers initially to differentiate epithelial ovarian carcinoma from benign gynecological conditions prior to surgery, so as to ensure appropriate surgical referral, and then to monitor the clinical course of disease during and after adjuvant therapy. The most commonly performed tumor marker assay in ovarian cancer (CA125) has been extremely valuable in patient management, but this marker is also elevated in a considerable proportion of..

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