Journal article

Mechanisms of abnormal gene expression in tumor cells.

Assam El-Osta

EXS | Published : 2006


Epigenetic mechanisms are involved in critical nuclear processes such as transcriptional control, genome stability, replication and repair. Recent evidence suggests that changes in the epigenetic repertoire can drive tumorigenesis. This review examines the latest experimental evidence that questions the mechanisms underlying the consequence of epigenetic changes in gene regulation and cancer development.

University of Melbourne Researchers