The NS segment of H5N1 avian influenza viruses (AIV) enhances the virulence of an H7N1 AIV in chickens
Julia Vergara-Alert, Nuria Busquets, Maria Ballester, Aida J Chaves, Raquel Rivas, Roser Dolz, Zhongfang Wang, Stephan Pleschka, Natalia Majo, Fernando Rodriguez, Ayub Darji
Veterinary Research | BMC | Published : 2014
Awarded by Spanish Government
Awarded by FPI-MICINN
Awarded by German Research Foundation (DFG)
Awarded by German Ministry for Education and Research (BMBF)
The authors thank M. Perez, R. Valle, B. Vidana and the personnel of the BSL-3 of CReSA for their excellent technical assistance. We also want to express our gratitude to Dr Mikhail Matrosovich for his critical reading and scientific discussion. This work was supported by the Spanish Government Grants AGL2007-60434/GAN and AGL2010-22229-C03-01 (Ministry of Science and Innovation, MICINN). J.V-A was supported by FPI-MICINN Training Grant BES-2008-00260. This work was also supported in part by grants from the German Research Foundation (DFG grant GRK1384, fellowship to Z.W.) and from the German Ministry for Education and Research funded "FluResearch-Net-Molecular Signatures Determining Pathogenicity and Species Transmission of Influenza A Viruses" (BMBF grant 01 KI 07136, to S.P.).