Genetic and environmental risk factors for chronic kidney disease.
Gregorio T Obrador, Ulla T Schultheiss, Matthias Kretzler, Robyn G Langham, Masaomi Nangaku, Roberto Pecoits-Filho, Carol Pollock, Jerome Rossert, Ricardo Correa-Rotter, Peter Stenvinkel, Robert Walker, Chih-Wei Yang, Caroline S Fox, Anna Köttgen
Kidney International Supplements | Published : 2017
In order to change the current state of chronic kidney disease knowledge and therapeutics, a fundamental improvement in the understanding of genetic and environmental causes of chronic kidney disease is essential. This article first provides an overview of the existing knowledge gaps in our understanding of the genetic and environmental causes of chronic kidney disease, as well as their interactions. The second part of the article formulates goals that should be achieved in order to close these gaps, along with suggested timelines and stakeholders that are to be involved. A better understanding of genetic and environmental factors and their interactions that influence kidney function in heal..View full abstract