Journal article

LOCATE: a mouse protein subcellular localization database

J Lynn Fink, Rajith N Aturaliya, Melissa J Davis, Fasheng Zhang, Kelly Hanson, Melvena S Teasdale, Chikatoshi Kai, Jun Kawai, Piero Carninci, Yoshihide Hayashizaki, Rohan D Teasdale

NUCLEIC ACIDS RESEARCH | OXFORD UNIV PRESS | Published : 2006

Abstract

We present here LOCATE, a curated, web-accessible database that houses data describing the membrane organization and subcellular localization of proteins from the FANTOM3 Isoform Protein Sequence set. Membrane organization is predicted by the high-throughput, computational pipeline MemO. The subcellular locations of selected proteins from this set were determined by a high-throughput, immunofluorescence-based assay and by manually reviewing >1700 peer-reviewed publications. LOCATE represents the first effort to catalogue the experimentally verified subcellular location and membrane organization of mammalian proteins using a high-throughput approach and provides localization data for approxim..

View full abstract

University of Melbourne Researchers