Chemotherapy response evaluation in metastatic colorectal cancer with FDG PET/CT and CT scans.
J Monteil, N Mahmoudi, S Leobon, PY Roudaut, A El Badaoui, S Verbeke, L Venat-Bouvet, J Martin, V Le Brun-Ly, S Lavau-Denes, A Maubon, P Bouillet, M Pouquet, JC Vandroux, N Tubiana-Mathieu
Anticancer Res | Published : 2009
BACKGROUND: [18F]-fluorodeoxyglucose with positron-emission tomography (PET) and computed tomography (CT) scans were used to assess morphological and metabolic tumour response after chemotherapy in metastatic colorectal cancer. PATIENTS AND METHODS: Twenty-five patients were evaluated after 4 courses of chemotherapy (+/-target therapy), and among them 20 patients after 2 courses. Response Evaluation Criteria In Solid Tumors (RECIST) and European Organisazion for Research and Treatment of Cancer (EORTC) criteria were used to evaluate CT and PET respectively. RESULTS: Discrepancies between the two procedures were noted after 4 courses of chemotherapy in patient-based analysis. Two morphologica..View full abstract