Effects of vitamin D supplementation on inflammatory markers in heart failure: a systematic review and meta-analysis of randomized controlled trials
Alexander J Rodriguez, Aya Mousa, Peter R Ebeling, David Scott, Barbora de Courten
Scientific Reports | NATURE PUBLISHING GROUP | Published : 2018
Vitamin D is reported to have anti-inflammatory properties; however the effects of vitamin D supplementation on inflammation in patients with heart failure (HF) have not been established. We performed a systematic review and meta-analysis examining effects of vitamin D supplementation on inflammatory markers in patients with HF. MEDLINE, CINAHL, EMBASE, All EBM, and Clinical Trials registries were systematically searched for RCTs from inception to 25 January 2017. Two independent reviewers screened all full text articles (no date or language limits) for RCTs reporting effects of vitamin D supplementation (any form, route, duration, and co-supplementation) compared with placebo or usual care ..View full abstract
Awarded by National Health and Medical Research Council R.D. Wright Biomedical Career Development Fellowship
Awarded by National Heart Foundation Future Leader Fellowship
AJR & AM are recipients of Australian Postgraduate Award Scholarships from Monash University. DS is supported by a National Health and Medical Research Council R.D. Wright Biomedical Career Development Fellowship (GNT1123014). BdC is supported by a National Heart Foundation Future Leader Fellowship (100864). We wish to thank the authors of the included articles for sending the required data for meta-analysis.