Journal article

Psychometric properties of outcome measures evaluating decline in gait in cerebellar ataxia: A systematic review

SC Milne, A Murphy, N Georgiou-Karistianis, EM Yiu, MB Delatycki, LA Corben

Gait and Posture | ELSEVIER IRELAND LTD | Published : 2018

Abstract

Cerebellar ataxia often results in impairment in ambulation secondary to gait pattern dysfunction and compensatory gait adjustments. Pharmaceutical and therapy-based interventions with potential benefit for gait in ataxia are starting to emerge, however evaluation of such interventions is hampered by the lack of outcome measures that are responsive, valid and reliable for measurement of gait decline in cerebellar ataxia. This systematic review aimed for the first time to evaluate the psychometric properties of gait and walking outcomes applicable to individuals with cerebellar ataxia. Only studies evaluating straight walking were included. A comprehensive search of three databases (MEDLINE, ..

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Grants

Awarded by Friedreich's Ataxia Research Alliance


Funding Acknowledgements

This study was supported by the Bruce Lefroy Centre (Murdoch Children's Research Institute), Friedreich Ataxia Association of Victoria, Friedreich Ataxia Research Association (Australasia) and the Friedreich Ataxia Research Alliance (United States of America). SM receives a National Health and Medical Research Council of Australia Postgraduate Scholarship (APP1093259). EY receives a National Health and Medical Research Council of Australia Early Career Fellowship (APP1073323). The supporting sources were not involved in the study design, analysis and interpretation of data, manuscript review; and decision to submit the article for publication.