Pleth Variability Index Predicts Fluid Responsiveness in Mechanically Ventilated Adults During General Anesthesia for Noncardiac Surgery
Andy Sisnata Siswojo, Daniel Mun-Yen Wong, Dien Phan Tuong, Roman Kluger
JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA | W B SAUNDERS CO-ELSEVIER INC | Published : 2014
OBJECTIVE: To investigate whether the pleth variability index (PVI), derived noninvasively from a pulse oximeter probe, would predict fluid responsiveness in patients undergoing noncardiac surgeries. DESIGN: A clinical, prospective, observational study. SETTING: Operating room of a tertiary care hospital. PARTICIPANTS: Twenty-nine adult patients undergoing a range of noncardiac surgeries, requiring general anesthesia, tracheal intubation, and mechanical ventilation. INTERVENTIONS: Intravenous volume expansion with 500 mL of colloid following induction of general anesthesia and after a period of hemodynamic stability before the start of surgery. MEASUREMENTS AND MAIN RESULTS: Baseline values ..View full abstract
This research was funded by the St. Vincent's Hospital (Melbourne) Research Endowment Fund.