Development of subcortical volumes across adolescence in males and females: A multisample study of longitudinal changes

MM Herting; C Johnson; KL Mills; N Vijayakumar; M Dennison; C Liu; AL Goddings; RE Dahl; ER Sowell; S Whittle; NB Allen; CK Tamnes

Journal article

Development of subcortical volumes across adolescence in males and females: A multisample study of longitudinal changes

MM Herting, C Johnson, KL Mills, N Vijayakumar, M Dennison, C Liu, AL Goddings, RE Dahl, ER Sowell, S Whittle, NB Allen, CK Tamnes

Neuroimage | Published : 2018

DOI: 10.1016/j.neuroimage.2018.01.020

Abstract

The developmental patterns of subcortical brain volumes in males and females observed in previous studies have been inconsistent. To help resolve these discrepancies, we examined developmental trajectories using three independent longitudinal samples of participants in the age-span of 8–22 years (total 216 participants and 467 scans). These datasets, including Pittsburgh (PIT; University of Pittsburgh, USA), NeuroCognitive Development (NCD; University of Oslo, Norway), and Orygen Adolescent Development Study (OADS; The University of Melbourne, Australia), span three countries and were analyzed together and in parallel using mixed-effects modeling with both generalized additive models and gen..

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University of Melbourne Researchers

Nandita Vijayakumar Author

Sarah Whittle Author

Nick Allen Author

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Grants

Awarded by National Institutes of Health

Funding Acknowledgements

This study was supported by the National Institutes of Health [R01 DA018910 (RED), R01 HD053893 and R01 MH087563 (ERS), F32 HD0708084 (MMH), K01 MH1087610 (MMH), R01 MH107418 (NV)]; the Research Council of Norway and the University of Oslo [FRIMEDBIO 230345 to CKT]; the Colonial Foundation, the National Health and Medical Research Council [NHMRC; Australia; Program Grant 350241; Career Development Fellowship 1007716 (SW)], the Australian Research Council [ARC; Discovery Grant DP0878136].