Cell of Origin of Small Cell Lung Cancer: Inactivation of Trp53 and Rb1 in Distinct Cell Types of Adult Mouse Lung
Kate D Sutherland, Natalie Proost, Inge Brouns, Dirk Adriaensen, Ji-Ying Song, Anton Berns
Cancer Cell | CELL PRESS | Published : 2011
Awarded by National Health and Medical Research Council of Australia
Awarded by Fund for Scientific Research-Flanders
We thank J. Zevenhoven, E. Riem, and J. van Ooij for their expert technical assistance; R. Kerkhoven for his expert help with performing array CGH analysis, and E. van Montfort for his assistance in interpreting the data; the personnel of the animal facility for their excellent animal husbandary; M. C. Kwon and P. Krimpenfort for critically reading the manuscript. We acknowledge J. Calbo for providing us with the mSCLC clonal cell lines; B. Stripp for providing us with the anti-CCSP antibody, S. Glasser for providing us with the mouse SP-C promoter, and R. I. Linnoila for kindly providing us with the mouse CC10 promoter and the rascal construct. K.D.S was a recipient of a National Health and Medical Research Council of Australia Overseas based Biomedical Training Fellowship (No. 516781). I.B. and D.A. are supported by the Fund for Scientific Research-Flanders (No. G.0081.08). This work was also supported by a grant of the Dutch Cancer Society.