Journal article
Renal artery anatomy affects the blood pressure response to renal denervation in patients with resistant hypertension
D Hering, P Marusic, AS Walton, J Duval, R Lee, Y Sata, H Krum, E Lambert, K Peter, G Head, G Lambert, MD Esler, MP Schlaich
International Journal of Cardiology | ELSEVIER IRELAND LTD | Published : 2016
Abstract
Background: Renal denervation (RDN) has been shown to reduce blood pressure (BP), muscle sympathetic nerve activity (MSNA) and target organ damage in patients with resistant hypertension (RH) and bilateral single renal arteries. The safety and efficacy of RDN in patients with multiple renal arteries remains unclear. Methods: We measured office and 24-hour BP at baseline, 3 and 6 months following RDN in 91 patients with RH, including 65 patients with single renal arteries bilaterally (group 1), 16 patients with dual renal arteries on either one or both sides (group 2) and 10 patients with other anatomical constellations or structural abnormalities (group 3). Thirty nine out of 91 patients com..
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Funding Acknowledgements
This study was funded in part by grants from the National Health and Research Council of Australia (NHMRC) and the Victorian Government's Operational Infrastructure Support Program with in-kind support by Medtronic. The funding organisations played no role in the design and conduct of the study, nor preparation or approval of the manuscript.