The small heat shock protein Hsp27 binds alpha-synuclein fibrils, preventing elongation and cytotoxicity
Dezerae Cox, Daniel R Whiten, James WP Brown, Mathew H Horrocks, Rebecca San Gil, Christopher M Dobson, David Klenerman, Antoine M van Oijen, Heath Ecroyd
Journal of Biological Chemistry | AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC | Published : 2018
Awarded by Australian Research Council Future Fellowship
Awarded by Australian Research Council Laureate Fellowship
This work was supported by grants from the Faculty of Science, Medicine and Health of the University of Wollongong and the Cambridge Centre for Mis-folding Diseases (to J.B. and C.M.D.). This work was also supported by an Australian Postgraduate Award (to D.C.), Australian Research Council Future Fellowship FT110100586 (to H.E.), and Australian Research Council Laureate Fellowship FL1401000027 (to. A.O.).