Is RNASEL:p.Glu265*a modifier of early-onset breast cancer risk for carriers of high-risk mutations?
Tu Nguyen-Dumont, Zhi L Teo, Fleur Hammet, Alexis Roberge, Maryam Mahmoodi, Helen Tsimiklis, Daniel J Park, Bernard J Pope, Andrew Lonie, Miroslav K Kapuscinski, Khalid Mahmood, David E Goldgar, Graham G Giles, Ingrid Winship, John L Hopper, Melissa C Southey
BMC Cancer | BIOMED CENTRAL LTD | Published : 2018
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Awarded by USA National Cancer Institute
Awarded by NHMRC
Awarded by USA National Institute of Health
Awarded by Victorian Life Sciences Computation Initiative grant
The ABCFR is the Australian site of the Breast Cancer Family Registry, and this work was supported by grant UM1 CA164920 from the USA National Cancer Institute. The content of the manuscript does not necessarily reflect the views or policies of the National Cancer Institute or any of the collaborating centres in the Breast Cancer Family Registry (BCFR), nor does mention of trade names, commercial products or organisations imply endorsement by the USA Government or the BCFR. The Australian Breast Cancer Family Registry was also supported by the Australian National Health and Medical Research Council (NHMRC), the New South Wales Cancer Council, the Victorian Health Promotion Foundation (Australia) and the Victorian Breast Cancer Research Consortium (VBCRC).This work was supported by the NHMRC (APP1025145), the USA National Institute of Health (RO1CA155767), the VBCRC and by a Victorian Life Sciences Computation Initiative grant (number VR0182) on its Peak Computing Facility, an initiative of the Victorian Government. TN-D is a National Breast Cancer Foundation (Australia) Career Development Fellow. ZLT was supported by Postgraduate Scholarships provided by the Faculty of Medicine, Dentistry and Health Sciences, The University of Melbourne and the NHMRC (Dora Lush Postgraduate Fellowship). AR was supported by a Bourse de Mobilite from Region Rhone-Alpes, France. JLH is a NHMRC Senior Principal Research Fellow and a VBCRC Group Leader. MCS is an NHMRC Senior Research Fellow and a VBCRC Group Leader. The funding bodies had no role in the design of the study and collection, analysis, and interpretation of data and in writing the manuscript.