Life After Surviving Fontan Surgery: A Meta-Analysis of the Incidence and Predictors of Late Death
CL Poh, Y d'Udekem
HEART LUNG AND CIRCULATION | ELSEVIER SCIENCE INC | Published : 2018
AIM: We now know that 20-40% of patients with a single ventricle will develop heart failure after the second decade post-Fontan surgery. However, we remain unable to risk-stratify the cohort to identify patients at highest risk of late failure and death. We conducted a systematic review of all reported late outcomes for patients with a Fontan circulation to identify predictors of late death. METHODS: We searched MEDLINE, Embase and PubMed with subject terms ("single ventricle", "Hypoplastic left heart syndrome", "congenital heart defects" or "Fontan procedure") AND ("heart failure", "post-operative complications", "death", "cause of death", "transplantation" or "follow-up studies") for relev..View full abstract
Dr CL Poh is supported by the Health Professional Scholarship from the National Heart Foundation of AustraliaProf Yves d'Udekem is a consultant for MSD and Actelion. He is an NHMRC Clinician Practitioner Fellow (1082186). The Victorian Government's Operational Infrastructure Support Program supported this research project.