Mass Spectrometry Using Nanomechanical Systems: Beyond the Point-Mass Approximation
John E Sader, M Selim Hanay, Adam P Neumann, Michael L Roukes
NANO LETTERS | AMER CHEMICAL SOC | Published : 2018
The mass measurement of single molecules, in real time, is performed routinely using resonant nanomechanical devices. This approach models the molecules as point particles. A recent development now allows the spatial extent (and, indeed, image) of the adsorbate to be characterized using multimode measurements ( Hanay , M. S. , Nature Nanotechnol. , 10 , 2015 , pp 339 - 344 ). This "inertial imaging" capability is achieved through virtual re-engineering of the resonator's vibrating modes, by linear superposition of their measured frequency shifts. Here, we present a complementary and simplified methodology for the analysis of these inertial imaging measurements that exhibits similar performan..View full abstract
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Awarded by ARC Centre of Excellence in Exciton Science
The authors acknowledge support from an NIH Director's Pioneer award, the Australian Research Council grants scheme, and the ARC Centre of Excellence in Exciton Science (CE170100026). M.S.H. acknowledges support from FP7 Marie Curie Career Integration Grant. The authors thank Mustafa Kara for useful discussion.