Journal article

Perforin proteostasis is regulated through its C2 domain: supra-physiological cell death mediated by T431D-perforin

Amelia J Brennan, Ruby HP Law, Paul J Conroy, Tahereh Noori, Natalya Lukoyanova, Helen Saibil, Hideo Yagita, Annette Ciccone, Sandra Verschoor, James C Whisstock, Joseph A Trapani, Ilia Voskoboinik

Cell Death & Differentiation | NATURE PUBLISHING GROUP | Published : 2018

Grants

Awarded by Wellcome Trust


Funding Acknowledgements

This work was supported by project and programme grants from the National Health and Medical Research Council of Australia (to IV, JCW and JAT), and Wellcome Trust equipment grant 079605 to HS. IV and JCW are supported by a National Health and Medical Research Council of Australia Fellowships. We thank Colin House and Conor Kearney for critical reading of the manuscript, and Mr Samuel J Redmond for his technical assistance.