Journal article
Accuracy of the Whooley questions and the Edinburgh Postnatal Depression Scale in identifying depression and other mental disorders in early pregnancy
LM Howard, EG Ryan, K Trevillion, F Anderson, D Bick, A Bye, S Byford, S O'Connor, P Sands, J Demilew, J Milgrom, A Pickles
British Journal of Psychiatry | CAMBRIDGE UNIV PRESS | Published : 2018
DOI: 10.1192/bjp.2017.9
Abstract
Background There is limited evidence on the prevalence and identification of antenatal mental disorders. Aims To investigate the prevalence of mental disorders in early pregnancy and the diagnostic accuracy of depression-screening (Whooley) questions compared with the Edinburgh Postnatal Depression Scale (EPDS), against the Structured Clinical Interview DSM-IV-TR. Method Cross-sectional survey of women responding to Whooley questions asked at their first antenatal appointment. Women responding positively and a random sample of women responding negatively were invited to participate. Results Population prevalence was 27% (95% CI 22-32): 11% (95% CI 8- 14) depression; 15% (95% CI 11-19) anxiet..
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Awarded by Manchester Biomedical Research Centre
Funding Acknowledgements
This paper summarises independent research funded by the National Institute for Health Research (NIHR) under the Programme Grants for Applied Research programme (ESMI Programme: grant reference number RP-PG-1210-12002) and the National Institute for Health Research (NIHR)/Wellcome Trust Kings Clinical Research Facility and the NIHR Biomedical Research Centre and Dementia Unit at South London and Maudsley NHS Foundation Trust and Kings College London. D.B. is supported by the National Institute for Health Research (NIHR) Collaboration for Leadership in Applied Health Research and Care South London at King's College Hospital NHS Foundation Trust (NIHR, CLAHRC-2013-10022). L.M.H. is also supported by a National Institute for Health Research (NIHR) Research Professorship (NIHR-RP-R32-011). The views expressed are those of the author(s) and not necessarily those of the NHS, the NIHR or the Department of Health. The study team acknowledges the study delivery support given by the South London Clinical Research Network.