A water-soluble, AIE-active polyelectrolyte for conventional and fluorescence lifetime imaging of mouse neuroblastoma neuro-2A cells

Y Wang; H Yao; J Zhou; Y Hong; B Chen; B Zhang; TA Smith; WWH Wong; Z Zhao

Journal article

A water-soluble, AIE-active polyelectrolyte for conventional and fluorescence lifetime imaging of mouse neuroblastoma neuro-2A cells

Y Wang, H Yao, J Zhou, Y Hong, B Chen, B Zhang, TA Smith, WWH Wong, Z Zhao

Journal of Polymer Science Part A Polymer Chemistry | Published : 2018

DOI: 10.1002/pola.28943

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Abstract

A new conjugated polyelectrolyte containing tetraphenylethene units in the backbone is synthesized and characterized. This polyelectrolyte is water-soluble and exhibits aggregation-induced emission (AIE) behavior. It is biocompatible and can be directly used in conventional and fluorescence lifetime imaging of mouse neuroblastoma neuro-2A cells, providing useful information of cellular morphology and intracellular aggregation or motion. © 2018 Wiley Periodicals, Inc. J. Polym. Sci., Part A: Polym. Chem. 2018, 56, 672–680.

University of Melbourne Researchers

Trevor Smith Author

Wallace Wong Author

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Grants

Awarded by National Natural Science Foundation of China

Funding Acknowledgements

We acknowledge the financial support from the National Natural Science Foundation of China (21404029, 21344007, and 21673082), the China Scholarship Council (201409645002), the Guangdong Natural Science Funds for Distinguished Young Scholar (2014A030306035), Scientific Research Fund of Zhejiang Provincial Education Department (Y201121319), and the Fundamental Research Funds for the Central Universities (2017ZD001).