Chimeric antigen receptor T cells form nonclassical and potent immune synapses driving rapid cytotoxicity
AJ Davenport, RS Cross, KA Watson, Y Liao, W Shi, HM Prince, PA Beavis, JA Trapani, MH Kershaw, DS Ritchie, PK Darcy, PJ Neeson, MR Jenkins
Proceedings of the National Academy of Sciences | NATL ACAD SCIENCES | Published : 2018
We thank Sarah Ellis, Jill Danne, Chad Johnson, and Kylie Luong for assistance with microscopy; Ralph Rossi, Viki Milovac, and Sophie Curcio for assistance with flow cytometry; the animal facility technicians (Peter MacCallum Cancer Centre) for help with animal care; Melissa Henderson (Peter MacCallum Cancer Centre) for technical support; and Han Xian Aw Yeang for proofreading the manuscript. M.R.J. is supported by a National Health and Medical Research Council of Australia (NHMRC) career development fellowship and an NHMRC New Investigator Project Grant. A.J.D. is supported by a Fight Cancer Foundation PhD Scholarship. J.A.T. and P.J.N. are supported by an NHMRC Program Grant. P.K.D. is supported by an NHMRC Senior Research Fellowship. W.S. is supported by a Walter and Eliza Hall Institute Centenary Fellowship funded by Commonwealth Serum Laboratories.