Journal article

Neurological effects of iron supplementation in infancy: finding the balance between health and harm in iron-replete infants

Dominic J Hare, Barbara Rita Cardoso, Ewa A Szymlek-Gay, Beverley-Ann Biggs

The Lancet Child & Adolescent Health | ELSEVIER SCI LTD | Published : 2018

Abstract

Iron mediates many biochemical processes in neural networks that proliferate during brain development. Insufficient iron causes irreversible neurodevelopmental deficits, and most high-income countries recommend that infants older than 4-6 months receive additional iron via food fortification or supplementation to prevent iron-deficiency anaemia. Now that the prevalence of iron-deficiency anaemia in children has decreased to less than 10% in most developed countries, concerns that the recommended intakes far exceed those required to prevent iron-deficiency anaemia have been raised, and emerging evidence suggests that iron overexposure could be linked to adverse outcomes later in life. In this..

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University of Melbourne Researchers