Journal article

Determining Brain Mechanisms that Underpin Analgesia Induced by the Use of Pain Coping Skills

Leonie J Cole, Kim L Bennell, Yasmin Ahamed, Christina Bryant, Francis Keefe, G Lorimer Moseley, Paul Hodges, Michael J Farrell

PAIN MEDICINE | OXFORD UNIV PRESS | Published : 2018

Abstract

Objective: Cognitive behavioral therapies decrease pain and improve mood and function in people with osteoarthritis. This study assessed the effects of coping strategies on the central processing of knee pain in people with osteoarthritis of the knees. Methods: Mechanical pressure was applied to exacerbate knee pain in 28 people with osteoarthritis of the knee. Reports of pain intensity and functional magnetic resonance imaging measures of pain-related brain activity were recorded with and without the concurrent use of pain coping skills. Results: Coping skills led to a significant reduction in pain report (Coping = 2.64 ± 0.17, Not Coping = 3.28 ± 0.15, P < 0.001). These strategies were ass..

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Grants

Awarded by National Health and Medical Research Council (NHMRC) Program Grant


Awarded by NHMRC Principal Research Fellowship


Awarded by NHMRC Senior Principal Research Fellowship


Awarded by NHMRC Principle Research Fellowship


Funding Acknowledgements

This study was supported by an National Health and Medical Research Council (NHMRC) Program Grant (#631717). Kim Bennell is also supported by an NHMRC Principal Research Fellowship (#1058440), Paul Hodges is supported by an NHMRC Senior Principal Research Fellowship (1002190), and Lorimer Moseley is supported by an NHMRC Principle Research Fellowship (#1061279). Lorimer Moseley consults for Pfizer, Kaiser Permanente, Providence Health Care, and Workers' Compensation Boards in Australia and North America. He receives payments for lectures and courses on pain and rehabilitation, and he receives royalties for several books on pain. The other authors declare no actual or potential conflicts of interest.