Journal article

Antibiotic Prophylaxis for Children With Sickle Cell Anemia

Sarah L Reeves, Alison C Tribble, Brian Madden, Gary L Freed, Kevin J Dombkowski

PEDIATRICS | AMER ACAD PEDIATRICS | Published : 2018

Abstract

BACKGROUND: Children with sickle cell anemia (SCA) are at increased risk for invasive pneumococcal disease; antibiotic prophylaxis significantly reduces this risk. We calculated the proportion of children with SCA who received ≥300 days of antibiotic prophylaxis and identified predictors of such receipt. METHODS: Children aged 3 months to 5 years with SCA were identified by the presence of 3 or more Medicaid claims with a diagnosis of SCA within a calendar year (2005-2012) in Florida, Illinois, Louisiana, Michigan, South Carolina, and Texas. Receipt of antibiotics was identified through claims for filled prescriptions. The outcome, receipt of ≥300 days of antibiotics, was assessed annually b..

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Grants

Awarded by Centers for Medicare and Medicaid Services under the Children's Health Insurance Program Reauthorization Act Pediatric Quality Measures Program Centers of Excellence


Funding Acknowledgements

Supported by the Agency for Healthcare Research and Quality and the Centers for Medicare and Medicaid Services under the Children's Health Insurance Program Reauthorization Act Pediatric Quality Measures Program Centers of Excellence grant U18 HS020516.